Fractionation of neurophysin by molecular-sieve and ion-exchange chromatography
- 1 July 1967
- journal article
- research article
- Published by Portland Press Ltd. in Biochemical Journal
- Vol. 104 (1) , 122-127
- https://doi.org/10.1042/bj1040122
Abstract
Neurophysin has been separated into 7 distinct protein fractions. One of these components had no hormone-binding activity. The fractions that had hormone-binding activity were similar in amino acid composition: their cystine content was in the range 11.5-14.5%. The major component, neurophysin-M, was dis-tinguished from the protein isolated by van Dyke by the presence of methionine and the absence of histidine. Neurophysin-M binds both oxytocin and vasopressin with similar affinities.This publication has 14 references indexed in Scilit:
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