Studies on the Antibacterial Action of Human Saliva. II. Observations on the Mode of Action of a Lactobacillus Bactericidin

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Abstract
The lethal effect of a salivary lactobacillus bactericidin on actively multiplying Lactobacillus acidophilus ATCC 4357 is apparently due to unbalanced growth. This was supported by the observation that killing of the organism was not accomplished by the saliva until an initial period of multiplication had occurred, and that the antibacterial factor was without obvious effect upon resting organisms. The bactericidin does not appear to alter the morphology or Gram reaction of the organism. It is not adsorbed by the organism.

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