Synthesis of cycloalkynes via photochemical decarboxylation of ω-phthalimidoalkynoates
- 20 January 2004
- journal article
- research article
- Published by Springer Nature
- Vol. 3 (3) , 311-316
- https://doi.org/10.1039/b312263h
Abstract
The photodecarboxylation reactions of ω-phthalimidoalkynoates have been studied and the influence of the geometrically restricted acetylene linker on the photocyclization efficiency investigated. Less flexible starting materials give solely CO2H/H-exchange products in good yields. In contrast, derivatives with appropriate chain lengths give the corresponding macrocycles in fair to moderate isolated yields. Furthermore, photodecarboxylative addition of alkynoates to N-methylphthalimide gives hydroxyphthalimidines in acceptable yields.Keywords
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