THE EFFECT OF FLOW RATE AND OSMOLARITY OF LUMEN CONTENTS ON CALCIUM AND WATER ABSORPTION FROM THIRY-VELLA FISTULAS IN DOGS
- 1 January 1963
- journal article
- Published by Canadian Science Publishing in Canadian Journal of Biochemistry and Physiology
- Vol. 41 (1) , 127-130
- https://doi.org/10.1139/y63-017
Abstract
The effect of a number of factors which locally might affect intestinal absorption of calcium in vivo was studied. Changes of osmolarity or of sodium concentration altered neither the calcium absorption rate nor the maximal absorptive capacity found at higher calcium concentrations. Under static conditions in a healed jejunal loop, calcium was absorbed more rapidly at first, but after 40 minutes the rate of absorption was essentially constant. Water absorption was approximately constant throughout the 2 hours. On the other hand, when the solutions flowed slowly through the gut loop, calcium was absorbed six times, and water four times more rapidly. The importance of these findings to normal absorption is discussed.Keywords
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