How do germ cells choose their sex? Drosophila as a paradigm
- 1 August 1992
- Vol. 14 (8) , 513-518
- https://doi.org/10.1002/bies.950140803
Abstract
Sex determination in the germ line may either rely on cell‐autonomous genetic information, or it may be imposed during development by inductive somatic signals. In Drosophila, both mechanisms contribute to ensure that germ cells are oogenic when differentiating in females and spermatogenic when differentiating in males. Some of the genes that are involved in germ line sex determination have been identified. In other species, including vertebrates, inductive signals are commonly used to determine the sex of germ cells.Keywords
This publication has 40 references indexed in Scilit:
- The primary sex determination signal of Drosophila acts at the level of transcriptionCell, 1992
- Germ-line sex determination in Drosophila melanogasterTrends in Genetics, 1990
- bag-of-marbles: a Drosophila gene required to initiate both male and female gametogenesis.Genes & Development, 1990
- Sex Determination in Drosophila melanogasterThe Quarterly Review of Biology, 1990
- Sex in flies: the splice of lifeNature, 1989
- The role of the otu Gene in Drosophila oogenesisBioEssays, 1988
- The Drosophila sex determination gene daughterless has different functions in the germ line versus the somaCell, 1987
- Mutations affecting dosage compensation in Drosophila melanogaster: Effects in the germlineDevelopmental Biology, 1986
- Clonal analysis of the tissue specificity of recessive female-sterile mutations of Drosophila melanogaster using a dominant female-sterile mutation Fs(1)K1237Developmental Biology, 1983
- Autosomal mutations that interfere with sex determination in somatic cells of Drosophila have no direct effect on the germlineDevelopmental Biology, 1982