THE INFLUENCE OF ANOXIA ON THE ABSORPTION OF SODIUM CHLORIDE AND SODIUM SULPHATE FROM THE SMALL INTESTINE

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Abstract
The effect of various degrees of anoxia was studied on the absorption of equal parts of isotonic NaCl and isotonic Na2SO4 solns. from the small intestine of barbitalized dogs. The same technique was used as that reported by Van Liere et al in previous papers on absorption studies. The Cl ion is absorbed from the intestine against a diffusion gradient in the presence of a polyvalent anion and the Cl ion is absorbed more rapidly under these conditions than from a more concentrated soln. (0.9%) of NaCl alone. Anoxia reduced but did not prevent the facilitation of the Cl ion against a diffusion gradient, showing that this facilitation presumably does not depend critically upon the supply of O2 at tensions compatible with the life of the animal. Severe degrees of anoxia had no appreciable influence on the absorption of Na2SO4 from the mammalian small intestine.

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