Avian Lymphomatosis. IV. Pathogenesis

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Abstract
The clinical signs and pathological course of experimental avian lymphomatosis due to JM virus are described. The signs and lesiens are similar to those seen in field outbreaks. The lesions mainly consisted of proliferated cells originating from the primitive mesenchymal cells of the tunica adventitia of the arterioles, neurilemmal cells, and the lining cells of the hepatic sinusoids, in descending order of incidence. Concomitantly involved were the neural, visceral, and ocular systems.