Assessment of DNA double-strand breaks and γH2AX induced by the topoisomerase II poisons etoposide and mitoxantrone
- 25 March 2008
- journal article
- Published by Elsevier in Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis
- Vol. 641 (1-2) , 43-47
- https://doi.org/10.1016/j.mrfmmm.2008.03.005
Abstract
No abstract availableKeywords
This publication has 43 references indexed in Scilit:
- Roles of DNA topoisomerase II isozymes in chemotherapy and secondary malignanciesProceedings of the National Academy of Sciences, 2007
- Perturbed gap-filling synthesis in nucleotide excision repair causes histone H2AX phosphorylation in human quiescent cellsJournal of Cell Science, 2007
- The cellular control of DNA double‐strand breaksJournal of Cellular Biochemistry, 2006
- H2AX phosphorylation within the G 1 phase after UV irradiation depends on nucleotide excision repair and not DNA double-strand breaksProceedings of the National Academy of Sciences, 2006
- Roles of nonhomologous end-joining pathways in surviving topoisomerase II–mediated DNA damageMolecular Cancer Therapeutics, 2006
- Assessment of ATM phosphorylation on Ser‐1981 induced by DNA topoisomerase I and II inhibitors in relation to Ser‐139‐histone H2AX phosphorylation, cell cycle phase, and apoptosisCytometry Part A, 2005
- DNA Damage Induced by DNA Topoisomerase I- and Topoisomerase II- Inhibitors Detected by Histone H2AXphosphorylation in Relation to the Cell Cycle Phase and ApoptosisCell Cycle, 2003
- Involvement of H2AX in the DNA Damage and Repair ResponseCancer Biology & Therapy, 2003
- 26 S Proteasome-mediated Degradation of Topoisomerase II Cleavable ComplexesJournal of Biological Chemistry, 2001
- Are topoisomerase II inhibitor-induced micronuclei in vitro a predictive marker for the compounds' ability to cause secondary leukemias after treatment?Toxicology Letters, 1998