FACTOR XIII (FIBRIN STABILISING FACTOR) IN HENOCH‐SCHÖNLEIN'S PURPURA
- 1 May 1977
- journal article
- research article
- Published by Wiley in Acta Paediatrica
- Vol. 66 (3) , 273-277
- https://doi.org/10.1111/j.1651-2227.1977.tb07893.x
Abstract
In 13 of 17 consecutive children with Henoch-Schoenlein''s purpura the factor XIII determined with the dansyl cadaverine method was decreased during the acute phase. The decrease was assumed to be due to a specific degradation by proteolytic enzymes liberated from inflammatory cells, with defective local hemostasis as a result. Treatment with factor XIII combined with an antifibrinolytic drug controlled life-threatening gastrointestinal bleeding in 1 of the patients. Such treatment might offer a new possibility of controlling severe hemorrhages in Henoch-Schoenlein''s purpura.Keywords
This publication has 22 references indexed in Scilit:
- Generalized Proteolysis in a Young Woman with Weber-Christian Disease (Nodular Nonsuppurative Panniculitis)Scandinavian Journal of Haematology, 2009
- Erosive Hemorrhagic Gastroduodenitis with Fibrinolysis and Low Factor XIIIAnnals of Surgery, 1975
- Immunologic Studies in Haemophilia AScandinavian Journal of Haematology, 1973
- Plasmin Digestion of Stabilized and Non-Stabilized Fibrin Illustrated by pH-Stat Titration and ThrombelastographyScandinavian Journal of Clinical and Laboratory Investigation, 1971
- Diagnostic and genetic studies on fibrin-stabilizing factor with a new assay based on amine incorporationJournal of Clinical Investigation, 1969
- Inhibitors of Fibrin Cross-linking : Relevance for ThrombolysisNature, 1966
- Accelerated Lysis of Blood ClotsNature, 1962
- A Method for Determining Serum Inhibitors of Plasminogen ActivationScandinavian Journal of Clinical and Laboratory Investigation, 1962
- On an Inherited Autosomal Hemorrhagic Diathesis with Antihemophilic Globulin (AHG) Deficiency and Prolonged Bleeding Times1Acta Medica Scandinavica, 1957