Immunological Aspects of Epilepsy
- 1 October 1980
- Vol. 21 (5) , 451-457
- https://doi.org/10.1111/j.1528-1157.1980.tb04295.x
Abstract
Epileptogenic activity can be provoked in animals by topical application on the cerebral cortex of antiserum to brain tissue. Several patients with epilepsy have an immunoglobulin A (IgA) deficiency, which may be caused by antiepileptic drugs (drug-induced) or may apparently be associated with the epileptic condition (drug-independent). Deficiency of secretory IgA may pre-dispose the patients for recurrent upper respiratory infections. Some antiepileptic drugs may also reduce the number of circulating T-lymphocytes.Keywords
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