The Structure of the Chromosomes of the Salivary Gland of Drosophila melanogaster

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Abstract
Chromosomes fixed in butyric carmine show chromonemata more clearly than those fixed in aceto-carmine, and each chromatin band is converted into a transverse row of chromioles. Propionic carmine gives similar results. X-ray treatment of eggs results in deficiencies in adjacent pairs of chromatic bands, these in turn possibly caused by the inactivation of a unit in the achromatic region. Chromosome abnormalities are the result of indirect, not direct, effect of irradiation, since irradiation of older larvae produces no visible effects. The last normal mitosis apparently occurs 6-8 hrs. after the egg is laid. The gene appears to be located on the chromonema between the chromioles.