Use of L‐asparaginase and cytosine arabinoside for refractory acute lymphocytic leukemia with particular reference to T‐cell leukemia

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Abstract
Ten patients with late‐stage acute lymphocytic leukemia were treated with L‐asparaginase and cytosine arabinoside. Complete remission was achieved in 8 patients including 5 of 5 patients with T‐cell leukemia. Major toxicity included anaphylactic reactions in 3 of the 10 patients.