The X-ray crystal and molecular structure of neohesperidin dihydrochalcone sweetener
- 1 January 1986
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Perkin Transactions 1
- No. 5,p. 843-848
- https://doi.org/10.1039/p19860000843
Abstract
The molecular structure and absolute configuration of the sweetener neohesperidin dihydrochalcone have been determined by single-crystal X-ray analysis. The crystal structure consists of two crystal-lographically independent molecules which differ mainly in the orientation of the isovanillyl B-ring. The molecules are linked together by an intricate arrangement of intermolecular hydrogen bonds formed between the host and solvent water molecules. The relation between the X-ray-deduced structure of the sweetener and a hypothetical ‘active’ conformation is discussed.This publication has 3 references indexed in Scilit:
- Structure-taste correlations for flavans and flavanones conformationally equivalent to phyllodulcinJournal of Agricultural and Food Chemistry, 1981
- Dihydrochalcone sweeteners. Synthesis and sensory evaluation of sulfonate derivativesJournal of Agricultural and Food Chemistry, 1977
- Molecular Theory of Sweet TasteNature, 1967