Hemoglobin F-Caltech: α22120Lys→Gln

Abstract
During cord blood screening, a fast moving .gamma.-chain variant was detected in an infant of French-Swedish-Hispanic extraction. In this variant, lysine at residue 120 (GH 3) in the G.gamma. chain is replaced by glutamine. Because the A.gamma.T chain is also present, this girl has 4 types of .gamma. chain. The percentage is unusually high for a .gamma.-chain variant.