Acquired Functional Asplenia
- 1 June 1980
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of internal medicine (1960)
- Vol. 140 (6) , 844-845
- https://doi.org/10.1001/archinte.1980.00330180118035
Abstract
A 45-year-old woman who had lower extremity ecchymoses and vague abdominal and back complaints was found to have acquired functional asplenia manifested by Howell-Jolly bodies and poikilocytosis on peripheral blood smear. On spleen scan there was inability to take up radioactive colloid. Shortly thereafter, she was found to have a spontaneous rupture of the spleen. At operation, the spleen, liver, and periaortic lymph nodes were found to be diffusely involved with amyloidosis. Five months later, an acute, serious, intra-abdominal condition developed secondary to spontaneous rupture of the liver, and the patient died. To our knowledge, neither acquired functional asplenia nor spontaneous rupture of the liver has been reported previously in association with amyloidosis. (Arch Intern Med 140:844-845, 1980)This publication has 3 references indexed in Scilit:
- Rupture of the Spleen in AmyloidosisPublished by American Medical Association (AMA) ,1979
- Severe intrahepatic cholestasis in primary amyloidosis. a report of four cases and a review of the literatureThe American Journal of Medicine, 1978
- PRIMARY AMYLOIDOSIS WITH SPONTANEOUS RUPTURE OF THE SPLEEN AND SUDDEN DEATHAnnals of Internal Medicine, 1955