Synthesis and evaluation of deglycobleomycin A2 analogues containing a tertiary N-methyl amide and simple ester replacement for the l-histidine secondary amide: Direct functional characterization of the requirement for secondary amide metal complexation
- 29 February 1996
- journal article
- research article
- Published by Elsevier in Bioorganic & Medicinal Chemistry
- Vol. 4 (2) , 179-193
- https://doi.org/10.1016/0968-0896(95)00183-2
Abstract
No abstract availableKeywords
This publication has 70 references indexed in Scilit:
- Solution Structure of a Zn(II).cntdot.Bleomycin A5-d(CGCTAGCG)2 ComplexJournal of the American Chemical Society, 1994
- Interaction of Co.cntdot.Bleomycin A2 (Green) with d(CCAGGCCTGG)2: Evidence for Intercalation Using 2D NMRJournal of the American Chemical Society, 1994
- Deglyco GABA-Gly-desacetamidobleomycin A2: a simplified synthetic model for bleomycin A2Bioorganic & Medicinal Chemistry Letters, 1992
- P-3A and (−)-desacetamido P-3A: demonstration and Study of their effective functional cleavage of duplex DNABioorganic & Medicinal Chemistry Letters, 1992
- A simple method for the purification and isolation of bleomycin A2Bioorganic & Medicinal Chemistry Letters, 1992
- The role of redox-active metals in the mechanism of action of bleomycinChemico-Biological Interactions, 1990
- Locations of nucleosomes on the regulatory region of simian virus 40 chromatinJournal of Molecular Biology, 1989
- Nature of carbon monoxide binding of iron(II)‐bleomycinFEBS Letters, 1985
- Basische Peptide des Bienengifts, II. Synthese zweier Pentapeptide aus der Sequenz des Mastzellen-degranulierenden PeptidsHoppe-Seyler´s Zeitschrift Für Physiologische Chemie, 1976
- Increased DNA chain breakage by combined action of bleomycin and superoxide radicalBiochemical and Biophysical Research Communications, 1975