Gastroduodenal mucosal surface and luminal pH in gastric ulcer
- 1 November 1991
- journal article
- research article
- Published by Springer Nature in Digestive Diseases and Sciences
- Vol. 36 (11) , 1543-1549
- https://doi.org/10.1007/bf01296395
Abstract
Gastroduodenal mucosal surface pH was measuredin situ by electrode in endoscopically normal and gastric ulcer patients. With the exception of the antrum, mucosal surface pH in the ulcer group (GU) resembled that of the endoscopically normal group. In contrast, the antral mucosal surface pH of the GU group of 7.06±0.11 (22) was significantly (PP<0.001) than the value of 6.98±0.18 (12) for gastric ulcer patients. Mucosal surface alkalinity of the GU antrum may be a response to damage but seems inappropriate in view of the likelihood of acid dependent inhibition of gastric acid secretion.Keywords
This publication has 30 references indexed in Scilit:
- Campylobacter pyloridisin Peptic Ulcer Disease: I. Gastric and Duodenal Infection Caused byC. pyloridis:Histopathologic and Microbiologic FindingsScandinavian Journal of Gastroenterology, 1987
- Synthesis of prostaglandin E2, thromboxane B2 and prostaglandin catabolism in gastritis and gastric ulcer.Gut, 1986
- Assessment of the ‘ mucus-bicarbonate ’ barrier in the stomach of patients with chronic gastric disordersClinica Chimica Acta; International Journal of Clinical Chemistry, 1984
- Demonstration of a pH gradient across the mucus layer on the surface of human gastric mucosa in vitro.Gut, 1982
- Mucus and bicarbonate secretion in the stomach and their possible role in mucosal protection.Gut, 1980
- pH OR HYDROGEN-ION CONCENTRATION IN STATISTICS?The Lancet, 1977
- Hyperosmotic instillation of rat stomachLife Sciences, 1975
- Variation in Size of the Gastric AntrumAnnals of Surgery, 1966
- THE pH FIELDS OF THE GASTRIC MUCOSAThe Lancet, 1962