SEPARATION IN THE BRAIN STEM OF THE MECHANISMS OF HEAT LOSS FROM THOSE OF HEAT PRODUCTION

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Abstract
In cats and dogs the mechanisms regulating heat production were eliminated with sparing of the mechanisms regulating heat loss by the following procedures (1) severing all descending fibers at the level of the pons except those passing in the extreme lateral position; (2) transection of the brain stem through the most caudal extent of the diencephalon, and (3) severing the hypothalamus from the lower brain stem. The results indicate that the central mechanisms regulating heat production and heat loss respectively are functionally independent, except for a probable reciprocal innervation; the structural elements in the cephalic brain stem subserving the heat loss and heat production mechanisms have separate loci to the extent that the former extends further caudad than do the latter; and the fibers descending from the heat loss elements have a greater lateral distribution at the level of the pons than do those descending from the heat production elements.

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