A simple immunochemical technique for distinguishing melanocytes and melanophages in paraffin-embedded tissue
- 1 April 1990
- journal article
- research article
- Published by Wiley in Journal of Cutaneous Pathology
- Vol. 17 (2) , 77-81
- https://doi.org/10.1111/j.1600-0560.1990.tb00060.x
Abstract
We describe an immunoperoxidase technique for distinguishing melanocytes and melanophages in paraffin-embedded tissue. Two primary antibodies were used: anti-S100 and HAM-56, a monoclonal antibody directed against macrophages. In a variety of pigmented lesions, HAM-56 labelled melanophages while S100 labelled cells of melanocytic lineage.This publication has 8 references indexed in Scilit:
- Identification of Factor XIIIa in cutaneous tissueHistopathology, 1988
- THE EXPRESSION OF PNA-LECTIN BINDING-SITES AND S-100 PROTEIN IN HISTIOCYTIC LESIONS OF THE SKIN - A COMPARATIVE IMMUNOHISTOCHEMICAL STUDY1988
- HUMAN ATHEROSCLEROSIS .2. IMMUNOCYTOCHEMICAL ANALYSIS OF THE CELLULAR COMPOSITION OF HUMAN ATHEROSCLEROTIC LESIONS1986
- A COMPARATIVE ULTRASTRUCTURAL-STUDY OF CUTANEOUS BLUE NEVI OF HUMANS AND HAMSTERS1986
- High melanosome engulfing activity of cutaneous fibroblasts in macular amyloidosis: an electron microscopic studyJournal of Cutaneous Pathology, 1984
- The Value of Immunohistochemical Studies Using Antibody to S100 Protein in DermatopathologyInternational Journal of Dermatology, 1984
- Demonstration of α1-antitrypsin and α1-antichymotrypsin in cutaneous histiocytic infiltrates and a comparison with intracellular lysozymeJournal of the American Academy of Dermatology, 1982
- The distribution of muramidase (lysozyme) in human tissues.Journal of Clinical Pathology, 1975