Nucleotide sequence of the ampicillin resistance gene of Escherichia coli plasmid pBR322.
- 1 August 1978
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 75 (8) , 3737-3741
- https://doi.org/10.1073/pnas.75.8.3737
Abstract
The nucleotide sequence of the ampicillin resistance gene of pBR322, an E. coli plasmid that encodes a penicillin .beta.-lactamase, was determined. This gene codes for a protein of 286 amino acid residues. The first 23 amino acids presumably form a signal for secretion, because they do not appear in the mature enzyme, whose partial amino acid sequence was determined independently.This publication has 20 references indexed in Scilit:
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