Advances in and applications of proteasome inhibitors
- 24 July 2008
- journal article
- review article
- Published by Elsevier in Current Opinion in Chemical Biology
- Vol. 12 (4) , 434-440
- https://doi.org/10.1016/j.cbpa.2008.06.033
Abstract
No abstract availableKeywords
This publication has 44 references indexed in Scilit:
- Engineered Biosynthesis of Antiprotealide and Other Unnatural Salinosporamide Proteasome InhibitorsJournal of the American Chemical Society, 2008
- Proteasome Inhibition by Fellutamide B Induces Nerve Growth Factor SynthesisChemistry & Biology, 2008
- Proteasome Inhibitors in Cancer Therapy: Lessons from the First DecadeClinical Cancer Research, 2008
- Combination of proteasome inhibitors bortezomib and NPI-0052 trigger in vivo synergistic cytotoxicity in multiple myelomaBlood, 2008
- Salinosporamide A (NPI-0052) potentiates apoptosis, suppresses osteoclastogenesis, and inhibits invasion through down-modulation of NF-κB–regulated gene productsBlood, 2007
- NPI-0052, a novel proteasome inhibitor, induces caspase-8 and ROS-dependent apoptosis alone and in combination with HDAC inhibitors in leukemia cellsBlood, 2007
- Genome sequencing reveals complex secondary metabolome in the marine actinomycete Salinispora tropicaProceedings of the National Academy of Sciences, 2007
- A novel proteasome inhibitor NPI-0052 as an anticancer therapyBritish Journal of Cancer, 2006
- Crystal Structures of Salinosporamide A (NPI-0052) and B (NPI-0047) in Complex with the 20S Proteasome Reveal Important Consequences of β-Lactone Ring Opening and a Mechanism for Irreversible BindingJournal of the American Chemical Society, 2006
- Salinosporamide A: A Highly Cytotoxic Proteasome Inhibitor from a Novel Microbial Source, a Marine Bacterium of the New Genus SalinosporaAngewandte Chemie International Edition in English, 2003