Localization of the thyroglobulin gene by in situ hybridization to human chromosomes
- 1 January 1985
- journal article
- research article
- Published by Springer Nature in Human Genetics
- Vol. 69 (1) , 28-31
- https://doi.org/10.1007/bf00295525
Abstract
The human thyroglobulin gene was mapped by in situ hybridization whereby a 3H-labeled recombinant plasmid DNA containing a fragment of 2.3 kilobases of human thyroglobulin gene was hybridized to human chromosome preparations. A high proportion (25%) of hybridized metaphases exhibited silver grains at the distal portion of the long arm of chromosome 8. Analysis of the grain position at this site indicated that the chromosomal localization of the human thyroglobulin gene was 8q242-8q243.Keywords
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