Double-blind trial of amoxycillin and ampicillin plus probenecid in the treatment of gonorrhoea in men.

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Abstract
In a double-blind study amoxycillin (3 g) or ampicillin (3 g) plus probenecid (1 g) were randomly administered as a single oral dose to 160 men with uncomplicated gonococcal urethritis. The cure rate for each drug group was 98.6%. Tolerance to oral medication was good and no evidence of allergy or toxicity to either drug was shown. No case of post-gonococcal urethritis was observed over a 14 day follow-up period. Both drug regimens proved very effective in treating uncomplicated gonococcal urethritis in men.