Krabbe disease: Increased incidence in a highly inbred community
- 1 August 1985
- journal article
- research article
- Published by Wiley in American Journal of Medical Genetics
- Vol. 21 (4) , 765-770
- https://doi.org/10.1002/ajmg.1320210420
Abstract
Krabbe disease (globoid cell leukodystrophy) was found with very high incidence (6/1,000 live births) in a large Druze kindred in Israel. The clinical data on 12 of the affected children demonstrated clinical variability even though these children are homozygous for the same mutation by descent from a common ancestor.Keywords
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