THE DIASTEREOSELECTIVE ADDITION OF TIN(II) ENOLATES DERIVED FROM CARBOXYLIC THIOESTERS TO α-IMINOESTER
- 5 June 1986
- journal article
- research article
- Published by Oxford University Press (OUP) in Chemistry Letters
- Vol. 15 (6) , 915-918
- https://doi.org/10.1246/cl.1986.915
Abstract
The diastereoselective addition of the Sn(II) enolates derived from carboxylic thioesters to α-iminoester is described. The Sn(II) enolates of t-butylthiol esters react smoothly with α-iminoester to afford the corresponding β-aminoacid derivatives in good yield with high diastereoselectivity.Keywords
This publication has 4 references indexed in Scilit:
- Stereocontrolled synthesis of (+)-thienamycin from 3(R)-hydroxybutyric acidTetrahedron Letters, 1985
- Synthetic control leading to chiral compoundsTetrahedron, 1984
- Two Simple Methods for the Synthesis of Trialkyl ?-Aminophosphono-Acetates ( 3 ). Trifluoromethanesulfonyl Azide as an Azide-Transfer AgentSynthetic Communications, 1980
- Syntheses of macrolide antibiotics. III. Direct ester and lactone synthesis from S-tert-butyl thioate (thiol ester)Journal of the American Chemical Society, 1975