AN IMMUNOGENETIC STUDY OF OLDER AGE ONSET RHEUMATOID-ARTHRITIS
- 1 January 1984
- journal article
- research article
- Vol. 11 (2) , 147-149
Abstract
Thirty-two patients with older age onset rheumatoid arthritis (ORA), defined as disease onset after age 60, were selected for HLA typing. The majority (69%) were rheumatoid factor (RF) seronegative. An increase in HLA-DR4, though not statistically significant, was seen in ORA (38% vs. 17% normals). This antigen was strongly associated with RF seropositivity (70%, P < 0.01) and rheumatoid nodules (75%, P < 0.01) in ORA. The immunogenetics of ORA are similar to that described for adult RA in general.This publication has 14 references indexed in Scilit:
- HLA-Bw44 and HLA-DRw4 in male Sjögren's syndrome patients with associated rheumatoid arthritisClinical Immunology and Immunopathology, 1980
- Hla antigens and rheumatoid arthritis association between hla‐drw4 positivity and igm rheumatoid factor productionArthritis & Rheumatism, 1980
- RHEUMATOID-ARTHRITIS AND LYMPHOCYTE-B ALLOANTIGEN HLA-DRW41980
- Recognition of a Non‐HLA‐ABC Antigen Present on B and T Lymphocytes and Monocytes only Detectable with the Indirect Immunofluorescence TestVox Sanguinis, 1979
- Association of the B-Cell Alloantigen DRw4 with Rheumatoid ArthritisNew England Journal of Medicine, 1978
- Increased Frequency of HLA‐Cw3 and HLA‐Dw4 in Rheumatoid ArthritisArthritis & Rheumatism, 1977
- Mixed lymphocyte cultures in rheumatoid arthritis.Journal of Clinical Investigation, 1976
- THE ONSET OF RHEUMATOID ARTHRITIS IN THE AGEDJournal of the American Geriatrics Society, 1967
- RHEUMATOID ARTHRITIS IN OLD AGE1966
- RHEUMATOID ARTHRITIS IN THE ELDERLYJournal of the American Geriatrics Society, 1956