Amino acids and peptides. XIV Synthesis and biological activity of three S-peptide analogues of bovine pancreatic ribonuclease A (RNase A).
- 1 January 1987
- journal article
- research article
- Published by Pharmaceutical Society of Japan in CHEMICAL & PHARMACEUTICAL BULLETIN
- Vol. 35 (2) , 468-478
- https://doi.org/10.1248/cpb.35.468
Abstract
Three S-peptide analogues of bovine pancreatic ribonuclease A (RNase A), [Nle1] [Lys7] S-peptide (I), [Lys1] [Nle7] S-peptide (II) and [Nle1] [Nle7] S-peptide (III), were synthesized by the fragment condensation method and their ability to reactivate S-protein was examined. It was found that Lys1 and Lys7 both have roles in the reactivation of S-protein.Keywords
This publication has 14 references indexed in Scilit:
- Studies on peptides. 103. Chemical synthesis of a crystalline protein with the full enzymic activity of ribonuclease AJournal of the American Chemical Society, 1981
- Total synthesis of bovine pancreatic ribonuclease A. Part 5. Synthesis of the protected S-protein (positions 21–124) and the protected S-peptide (positions 1–20)Journal of the Chemical Society, Perkin Transactions 1, 1981
- Total synthesis of bovine pancreatic ribonuclease A. Part 4. Synthesis of the protected tetraoctacontapeptide ester (positions 41–124)Journal of the Chemical Society, Perkin Transactions 1, 1981
- Total synthesis of bovine pancreatic ribonuclease A. Part 3. Synthesis of the protected hexapentacontapeptide ester (positions 69–124)Journal of the Chemical Society, Perkin Transactions 1, 1981
- Total synthesis of bovine pancreatic ribonuclease A. Part 2. Synthesis of the protected hexatriacontapeptide ester (positions 89–124)Journal of the Chemical Society, Perkin Transactions 1, 1981
- Total synthesis of bovine pancreatic ribonuclease A. Part 1. Synthesis of the protected pentadecapeptide ester (positions 110–124)Journal of the Chemical Society, Perkin Transactions 1, 1981
- The Reaction of Bovine Pancreatic Ribonuclease A with 6‐Chloropurineriboside 5′‐MonophosphateEuropean Journal of Biochemistry, 1980
- SIDE REACTIONS IN PEPTIDE-SYNTHESIS .6. RE-EXAMINATION OF BENZYL GROUP IN PROTECTION OF SIDE-CHAINS OF TYROSINE AND ASPARTIC-ACID1978
- SIDE REACTIONS IN PEPTIDE-SYNTHESIS .7. SEQUENCE DEPENDENCE IN FORMATION OF AMINOSUCCINYL DERIVATIVES FROM BETA-BENZYL-ASPARTYL PEPTIDES1978
- Structure and Function of RibonucleasePublished by Wiley ,1962