Lumbar transplant of neurons genetically modified to secrete brain-derived neurotrophic factor attenuates allodynia and hyperalgesia after sciatic nerve constriction
- 1 May 2000
- journal article
- Published by Wolters Kluwer Health in Pain
- Vol. 86 (1) , 195-210
- https://doi.org/10.1016/s0304-3959(00)00245-1
Abstract
Chronic delivery of anti-nociceptive molecules by means of cell grafts near the pain processing centers of the spinal cord is a newly developing technique for the treatment of neuropathic pain. The rat neuronal cell line, RN33B, derived from E13 rat brainstem raphe and immortalized with theKeywords
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