Experimental cutaneousCandida albicansinfection in guinea-pigs

Abstract
A characteristic infection pattern was observed in nonscarified adult guinea-pigs that had been artificially infected with Candida albicans, and injected with 1 dose of 200 mg/kg of alloxan. Lesions appeared less rapidly in nonscarified animals but within 8–15 days of the induced infection the lesions were maximal and were much more homogeneous than in scarified animals. The guinea-pig is an excellent laboratory model for the study of anticandidal substances.