ANTIBODY-MEDIATED SUPPRESSION OF TUMOR-GROWTH .2. MACROPHAGE AND PLATELET COOPERATION WITH MURINE IGG1 ISOLATED FROM ALLOANTISERUM

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  • 1 January 1977
    • journal article
    • research article
    • Vol. 118  (2) , 494-497
Abstract
The effectors that cooperate with IgG1 [immunoglobulin G1] in causing tumor [mouse 6C3HED lymphoma] suppression were identified as exudate macrophages and blood platelets in mice syngeneic and allogeneic to the tumor. Lymphocytes were not active in suppressing tumor growth in the presence of IgG1 antibody, although they were active with whole antiserum.