Sclerosing lymphangitis of the penis: a lymphangiofibrosis thrombotica occlusiva*

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Abstract
Three patients with non-venereal sclerosing lymphangitis of the penis are presented. Light microscopy and EM of 1 case revealed a lymphatic collecting vessel with a fibrin thrombus in the process of recanalization and vessel wall fibrosis due to hyperplasia of smooth muscle cells and fibroblasts. The term lymphangiofibrosis thrombotica occlusiva is proposed. Lymph stasis is suggested as a provoking factor for the dilatation and clinically striking firm thickening of the affected collecting vessel. No microorganisms were recognized. Within the fibrin thrombus, sprouts of endothelial cells showed intracellular vacuoles, probably indicating the 1st identifiable step in lymph capillary lumen formation. Signs of collagen remodelling were encountered in the thickened vessel wall.