Changes in Estrous Cycle of Rat During Prolonged Exposure to Cold.

Abstract
Studies on the reproductive activity of the adult female rat indicate that the length of the estrous cycle increased markedly following exposure to a low ambient temperature. Duration of both the proestrous and estrous stages was increased, whereas length of the metestrous and diestrous stages was decreased. Treatment with 50 ug of thyroxine prevented the abnormal changes in the estrous cycle during exposure to cold.

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