Enzyme-linked immunosorbent assay for detection of Clostridium botulinum type E toxin
- 1 June 1979
- journal article
- research article
- Published by American Society for Microbiology in Applied and Environmental Microbiology
- Vol. 37 (6) , 1173-1175
- https://doi.org/10.1128/aem.37.6.1173-1175.1979
Abstract
The enzyme-linked immunosorbent assay using the "double-sandwich" technique was utilized to determine Clostridium botulinum type E toxin. With this technique, about 80 mouse intraperitoneal 50% lethal doses of toxin could be detected. Cross-reaction was hardly observed with C. botulinum type A and B toxins. No cross-reaction was observed with culture supernatants of C. botulinum type C or other Clostridium strains. In all probability this was due to the high specificity of the antiserum prepared aginst the toxic component of type E toxin.This publication has 8 references indexed in Scilit:
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