PERSISTENCE OF TYPE-SPECIFIC ANTIBODIES IN MAN FOLLOWING INFECTION WITH GROUP A STREPTOCOCCI
Open Access
- 1 August 1959
- journal article
- research article
- Published by Rockefeller University Press in The Journal of Experimental Medicine
- Vol. 110 (2) , 271-292
- https://doi.org/10.1084/jem.110.2.271
Abstract
Whole blood or sera were collected from individuals who had had infections with Group A streptococci of known serological type as long ago as 10 to 32 years. Most of these patients had not been treated with chemotherapeutic drugs. By means of bactericidal tests with all these sera, and mouse protection tests with some, type-specific antibodies could be demonstrated in at least half of them after a lapse of many years, the longest interval being 32 years.Keywords
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