Screening for genetic abnormality
- 1 January 1989
- journal article
- research article
- Published by Cambridge University Press (CUP) in Fetal and Maternal Medicine Review
- Vol. 1 (01) , 13-25
- https://doi.org/10.1017/s096553950000005x
Abstract
Screening for genetic and congenital abnormalities during pregnancy has developed over the past 10–15 years from a concept to an established aspect of modern obstetric management in response to the declining importance of other causes of infant and perinatal mortality and morbidity. This review will consider why screening is indicated for this group of conditions, the criteria for any screening programme and the current impact of prenatal screening.Keywords
This publication has 42 references indexed in Scilit:
- Maternal serum unconjugated oestriol as an antenatal screening test for Down's syndromeBJOG: An International Journal of Obstetrics and Gynaecology, 1988
- Maternal Alpha-Fetoprotein Screening for Down's SyndromeNew England Journal of Medicine, 1987
- Screening for Fetal Down's Syndrome in Pregnancy by Measuring Maternal Serum Alpha-Fetoprotein LevelsNew England Journal of Medicine, 1987
- The impact of screening for open neural tube defects in England and WalesPrenatal Diagnosis, 1987
- Wessex Perinatal Mortality Survey 1982BJOG: An International Journal of Obstetrics and Gynaecology, 1985
- Congenital malformations in 10,000 consecutive births in a university hospital: Need for genetic counseling and prenatal diagnosisThe Journal of Pediatrics, 1984
- Antenatal screening for congenital nephrosis in Finland by maternal serum alpha-fetoproteinBJOG: An International Journal of Obstetrics and Gynaecology, 1983
- A cost-benefit analysis of a population screening programme for neural tube defectsPrenatal Diagnosis, 1983
- Congenital MalformationsNew England Journal of Medicine, 1983
- Estimating an individual's risk of having a fetus with open spina bifida and the value of repeat alpha-fetoprotein testing: FOURTH REPORT OF THE UK COLLABORATIVE STUDY ON ALPHA-FETOPROTEIN IN RELATION TO NEURAL TUBE DEFECTSJournal of Epidemiology and Community Health, 1982