Hepatitis and bone destruction as uncommon manifestations of early syphilis. Report of a case

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Abstract
A patient with a painful lytic lesion of the clavicle and a granuloma of the liver in late secondary syphilis is described. The classic moth-eaten alopecia of the scalp, eyebrows and eyelashes suggested syphilis, although an initial false-negative VDRL [veneral disease research laboratory] test for syphilis (prozone phenomenon) caused a delay in diagnosis. Bone and liver involvement in early syphilis may be more common than previously recognized.

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