DL-S-TRIFLUOROMETHYLHOMOCYSTEINE, A NOVEL INHIBITOR OF MICROBIAL GROWTH
- 1 February 1966
- journal article
- research article
- Published by Canadian Science Publishing in Canadian Journal of Microbiology
- Vol. 12 (1) , 143-148
- https://doi.org/10.1139/m66-020
Abstract
DL-S-Trifluoromethyl-homocysteine was tested for its effect on the growth of a wide variety of microorganisms. The compound, trifluoromethylhomocysteine, markedly inhibited growth of Mycobacterium smegmatis, Mycobacterium phlei, Candida lipolytica, Saccharomyces cerevisiae, Geotrichum candidum, and to a lesser extent, Candida albicans and Escherichia coli. In M. smegmatis glutamine, methionine, norleucine, norvaline, and certain natural products reversed this antagonism. Utilization of DL-methionine by Leuconostoc mesenteroides, a culture which re-quries preformed methionine, was not inhibited by trifluoromethylhomocysteine. The compound was also inactive as a replacement for methionine in growth of L. mesenteroides.This publication has 9 references indexed in Scilit:
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