Retroviruses and multiple sclerosis. II.
- 31 July 1990
- journal article
- research article
- Published by Wolters Kluwer Health in Neurology
- Vol. 40 (8) , 1254
- https://doi.org/10.1212/wnl.40.8.1254
Abstract
Multiple sclerosis (MS) has been associated with infection by a novel human retrovirus because of its similarity to other white matter diseases caused by retroviruses and because of some serologic evidence suggesting reactivity of MS sera with antigens of HTL V-I. With the polymerase chain reaction technique, we attempted to amplify genes of HTLV-I (p24 and pol) from lymphocyte and granulocyte DNA in 44 patients with MS, 18 other neurologic or autoimmune diseases, and 11 normal controls. With primers and probes specific for these genes, we were unable to identify sequences unique to patients with MS.This publication has 8 references indexed in Scilit:
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