HUNTINGTONS-DISEASE AND LEUKOCYTE ADHERENCE INHIBITION (LAI)
- 1 January 1981
- journal article
- research article
- Vol. 45 (3) , 583-589
Abstract
Patients with Huntington''s disease (HD) appear to possess a brain antigen not found in undiseased brain tissue. The tube leukocyte adherence inhibition (LAI) assay detects immunity to this putative antigen in individuals with Huntington''s disease (82%), multiple sclerosis (48%), other neurological disease (17%) and no neurological disease (16%). The antigen-like activity can be extracted from HD brain with 3 M KCl and precipitated with 65-80% saturated ammonium sulphate.This publication has 8 references indexed in Scilit:
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