Effect of testosterone cypionate on postexercise ST segment depression.

Publisher Website
Google Scholar
Abstract
A randomized double blind study was carried out with 50 men who had ST segment depression of 0.1 mV or more after a modified 2-step exercise test. Rate and duration of exercise were the same for the last of each subject''s several pretreatment tests as for his tests after 4 and 8 wk of treatment with placebo or testosterone cypionate, 200 mg, i.m. weekly. The sum of ST segment depression in leads II, V4, V5 and V6 taken immediately, and 2, 4 and 6 min after exercise did not change significantly after 4 or 8 wk of placebo treatment, but did decrease by 32% (P < 0.0001) and 51% (P < 0.0001) after 4 and 8 wk, respectively, of testosterone cypionate treatment. The mechanism by which testosterone cypionate treatment results in lessened postexercise ST segment depression is not established.