Structure-based design of irreversible, tripeptidyl human rhinovirus 3C protease inhibitors containing N-methyl amino acids
- 2 August 1999
- journal article
- Published by Elsevier in Bioorganic & Medicinal Chemistry Letters
- Vol. 9 (15) , 2189-2194
- https://doi.org/10.1016/s0960-894x(99)00368-6
Abstract
No abstract availableKeywords
This publication has 26 references indexed in Scilit:
- Tripeptide Aldehyde Inhibitors of Human Rhinovirus 3C Protease: Design, Synthesis, Biological Evaluation, and Cocrystal Structure Solution of P1 Glutamine Isosteric ReplacementsJournal of Medicinal Chemistry, 1998
- Inhibition of human rhinovirus 3C protease by homophthalimidesBioorganic & Medicinal Chemistry Letters, 1997
- Small peptidic aldehyde inhibitors of human rhinovirus 3C proteaseBioorganic & Medicinal Chemistry Letters, 1996
- Novel Triterpene Sulfates from Fusarium compactum Using a Rhinovirus 3C Protease Inhibitor Screen.The Journal of Antibiotics, 1996
- Design, Synthesis, and Evaluation of Nonpeptidic Inhibitors of Human Rhinovirus 3C ProteaseJournal of Medicinal Chemistry, 1996
- Glutamine-derived aldehydes for the inhibition of human rhinovirus 3C proteaseBioorganic & Medicinal Chemistry Letters, 1995
- Potent inhibitor of the human rhinovirus (HRV) 3C protease containing a backbone modified glutamineJournal of the Chemical Society, Perkin Transactions 1, 1995
- Structure of human rhinovirus 3C protease reveals a trypsin-like polypeptide fold, RNA-binding site, and means for cleaving precursor polyproteinCell, 1994
- Citrinin hydrate and radicinin: Human rhinovirus 3C-protease inhibitors discovered in a target-directed microbial screen.The Journal of Antibiotics, 1994
- Hydrolysis of a Series of Synthetic Peptide Substrates by the Human Rhinovirus 14 3C Proteinase, Cloned and Expressed in Escherichia coliJournal of General Virology, 1989