BLOOD AS A SITE FOR THE CONVERSION OF THE STEROID HORMONES1
- 1 January 1961
- journal article
- research article
- Published by The Endocrine Society in Endocrinology
- Vol. 68 (1) , 180-183
- https://doi.org/10.1210/endo-68-1-180
Abstract
Blood from bovine, guinea pig, baboon and human species was separately incubated or perfused through a glass cannula with hydrocortisone, estrone, or testosterone. Chromatographic analysis showed that each of the hormones undergoes alterations in chemical structure. The trend is towards the formation of biologically inactive forms. As little as ten minutes incubation time was enough to show conversion products, which are thought to be enzymatic in nature.Keywords
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