A CONTRIBUTION TO THE STUDY OF LINKAGE DISEQUILIBRIUM INDROSOPHILA MELANOGASTER

Publisher Website
Google Scholar
Abstract
Linkage disequilibrium was detected in 12 of 30 cases involving gene alleles and inversions in 3 cage populations and in a natural population of D. melanogaster from Greece. The cage populations possessed partically the same gene pool at their origin and were maintained simultaneously under the effects of the food medium and humidity. The correlation of the same direction found between the frequencies of nonallelic elements of Adh [alcohol dehydrogenase] locus and In(2L)22D-34A [inversion] or In(2R)52A-56F in such different populations as American, Japanese and Greek, as well as cage populations under different environmental conditions, could be attributed to the effect of epistatic selection. Moreover, it seems that the In(2L)22D-34A has a tendency to interact genetically with the .alpha.-Gpdh [.alpha.-glucophosphate dehydrogenase] locus, particularly when the populations are maintained under crowding conditions. However, further data are needed to assess whether the observed nonrandom associations can be better explained as transient associations generated by random drift, or as the result of epistatic selection.