RESERPINE AND CORTICOTROPHIN SECRETION
- 1 February 1966
- journal article
- research article
- Published by Oxford University Press (OUP) in Acta Endocrinologica
- Vol. 51 (2) , 203-209
- https://doi.org/10.1530/acta.0.0510203
Abstract
Reserpine counteracts the depressive effect of dexamethasone on adrenal weight and function. These data have been interpreted as indicating that the main effect of reserpine on the hypophysial-adrenal axis is that of enhancing rather than depressing corticotropin secretion. This might be achieved through the suppression of a mid-brain inhibitory action. The blocking of stress reactions induced by reserpine is thought to be a result of the feedback effects of the enhanced blood levels of adrenal steroids, induced by the drug.This publication has 14 references indexed in Scilit:
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