Hormonal Regulation of Pituitary Adrenocorticotrophin.
- 1 January 1958
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 97 (1) , 165-169
- https://doi.org/10.3181/00379727-97-23677
Abstract
A modification of the Saffran and Schally technique of in vitro bioassay of ACTH is described and evidence is presented for its precision, validity and reliability. Changes in pituitary ACTH content and concentration in rats after administration of various hormones for one week were studied by means of this technique. ACTH administration and adrenalectomy both resulted in a striking increase in pituitary ACTH content. Epinephrine and cortisone administration were both followed by significant depletion.Keywords
This publication has 12 references indexed in Scilit:
- Pituitary ACTH Content of Thyroidectomized-Stressed RatsAmerican Journal of Physiology-Legacy Content, 1955
- IN VITRO BIOASSAY OF CORTICOTROPIN: MODIFICATION AND STATISTICAL TREATMENTEndocrinology, 1955
- REDUCTION OF PITUITARY CONTENT OF ACTH BY CORTISONEEndocrinology, 1955
- AN IN VITRO ASSAY OF CORTICOTROPHINCanadian Journal of Biochemistry and Physiology, 1955
- BLOOD AND PITUITARY ACTH IN INTACT AND ADRENALECTOMIZED RATS AFTER STRESS1Endocrinology, 1954
- Blood and Pituitary Adrenocorticotrophin in Adrenalectomized Rats with Hypothalamic Lesions.Experimental Biology and Medicine, 1954
- DECREASE IN THE FORMATION OF ADRENOCORTICOTROPIN FOLLOWING ADMINISTRATION OF EPINEPHRINEEndocrinology, 1952
- INCREASE IN THE FORMATION AND SECRETION OF ACTH FOLLOWING ADRENALECTOMY1Endocrinology, 1951
- A SIMPLE METHOD FOR ANALYZING COMPLICATED ABSORPTION CURVES, OF USE IN THE COLORIMETRIC DETERMINATION OF URINARY STEROIDSJournal of Clinical Endocrinology & Metabolism, 1950
- Adrenalectomy and Pituitary Adrenocorticotrophic Hormone Content.Experimental Biology and Medicine, 1949