THE EFFECT OF SEDATIVES UPON DELAYED RESPONSE IN MONKEYS FOLLOWING REMOVAL OF THE PREFRONTAL LOBES
- 1 January 1947
- journal article
- research article
- Published by American Physiological Society in Journal of Neurophysiology
- Vol. 10 (1) , 57-61
- https://doi.org/10.1152/jn.1947.10.1.57
Abstract
Two monkeys, Macaca mulatta, performed delayed reactions with delays up to 35 secs. After removal of the prefrontal lobes this ability was lost. Given intraperit. injns. of Nembutal (8-10 mg./kg.) and Dial (25-30 mg./kg.) the animals performed delayed response up to 25 secs. After withdrawal of drugs, one animal continued to perform reliably above chance up to delays of 20 secs. in spite of the typical prefrontal hyperactivity.Keywords
This publication has 6 references indexed in Scilit:
- THE EFFECT OF ANTICONVULSANT DRUGS ON RECOVERY OF FUNCTION FOLLOWING CEREBRAL CORTICAL LESIONSJournal of Neurophysiology, 1945
- Problem solution by monkeys following bilateral removal of the prefrontal areas. V. Spatial delayed reactions.Journal of Experimental Psychology, 1945
- THE RELATION OF AREA 13 ON ORBITAL SURFACE OF FRONTAL LOBES TO HYPERACTIVITY AND HYPERPHAGIA IN MONKEYSJournal of Neurophysiology, 1943
- The effect of unilateral and bilateral frontal lobe extirpation on the behavior of monkeys.Journal of Comparative Psychology, 1942
- INTERFERENCE FACTORS IN DELAYED RESPONSE IN MONKEYS AFTER REMOVAL OF FRONTAL LOBESJournal of Neurophysiology, 1942
- NERVOUS CONTROL OF RESPIRATIONAmerican Journal of Physiology-Legacy Content, 1931