Membrane Topology and Nicastrin-enhanced Endoproteolysis of APH-1, a Component of the γ-Secretase Complex

This publication has 42 references indexed in Scilit:

• Aph-1, Pen-2, and Nicastrin with Presenilin Generate an Active γ-Secretase Complex
  Neuron, 2003
• The Amyloid Hypothesis of Alzheimer's Disease: Progress and Problems on the Road to Therapeutics
  Science, 2002
• γ-Secretase, notch, Aβ and alzheimer's disease: Where do the presenilins fit in?
  Nature Reviews Neuroscience, 2002
• Constitutive shedding of the amyloid precursor protein ectodomain is up-regulated by tumour necrosis factor-α converting enzyme
  Biochemical Journal, 2001
• Intramembrane proteolysis by presenilins
  Nature Reviews Molecular Cell Biology, 2000
• β-Secretase Cleavage of Alzheimer's Amyloid Precursor Protein by the Transmembrane Aspartic Protease BACE
  Science, 1999
• Evidence That Tumor Necrosis Factor α Converting Enzyme Is Involved in Regulated α-Secretase Cleavage of the Alzheimer Amyloid Protein Precursor
  Journal of Biological Chemistry, 1998
• Detection of a Novel Intraneuronal Pool of Insoluble Amyloid β Protein that Accumulates with Time in Culture
  The Journal of cell biology, 1998
• Alzheimer's Aβ(1–42) is generated in the endoplasmic reticulum/intermediate compartment of NT2N cells
  Nature Medicine, 1997
• Amyloid plaque core protein in Alzheimer disease and Down syndrome.
  Proceedings of the National Academy of Sciences, 1985