A role for clonal dominance in the maintenance of allotype suppression?
Open Access
- 1 October 1979
- journal article
- research article
- Published by Rockefeller University Press in The Journal of Experimental Medicine
- Vol. 150 (4) , 888-897
- https://doi.org/10.1084/jem.150.4.888
Abstract
The establishment of immunological memory during the early and complete phase of allotype suppression in the young rabbit has been shown to lead to the preferential production of antibodies with the nonsuppressed allotypic specificity in response to recall injections given after spontaneous or induced release from suppression. It is suggested that this manifestation of clonal dominance, applied to stimulation by environmental antigens, may contribute to the long lasting persistence of allotype imbalance in allotype suppressed rabbits.This publication has 16 references indexed in Scilit:
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