Liposome-bound cyclosporine: Aqueous and vitreous level after subconjunctival injection
- 1 January 1988
- journal article
- conference paper
- Published by Springer Nature in International Ophthalmology
- Vol. 12 (2) , 101-104
- https://doi.org/10.1007/bf00137133
Abstract
The concentration of cyclosporine in the aqueous and vitreous humors of albino rabbits was measured, using HPLC at intervals of 24, 48, 96, and 192 hours after subconjunctival injections of 2.5 mg of free or liposome-bound cyclosporine. The aqueous concentration was reasonably high in both groups until day 4: 1050 nanograms per milliliter in the group receiving free cyclosporine, and 1438 nanograms per milliliter in the group receiving liposome-bound cyclosporine. The vitreous concentration was very low in both groups.This publication has 15 references indexed in Scilit:
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