Achalasia sicca-juvenile Sjögren's syndrome with achalasia and gastric hyposecretion

1 January 1978

journal article
research article
Published by Springer Nature in European Journal of Pediatrics

Vol. 129 (3) , 175-181
https://doi.org/10.1007/bf00442161

Abstract

Sjögren's syndrome (SS) in its classical form, which includes kerato-conjunctivitis sicca, xerostomia and recurrent enlargement of the salivary glands, is associated with a connective tissue disease in at least half the patients. According to the present study of three patients with SS, achalasia and gastric hyposecretion seem to be either further manifestations of SS, or separate phenomena associated with SS. The gastric hyposecretion involves both the hydrochloric acid and the total volume of the secretion, but the gastric mucosa has a normal appearance on microscopy. Because of the simultaneous presence of achalasia, gastric hyposecretion and reduced salivation, we have called the combination “achalasia sicca”. The reduction in the secretions of the upper gastrointestinal tract might have a pathogenic association with achalasia.

Keywords

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